Med Minute: Cefdinir (Omnicef)

This Med Minute guide covers cefdinir (Omnicef), an antibiotic commonly used to treat bacterial infections like ear infections and acute bronchitis in adolescents. It works by stopping bacteria from growing and replicating, typically requiring a 7 to 10-day course. Keep reading for quick facts on uses, dosing, side effects, and tips for giving it to your child!

What's it commonly used for?

• Treating bacterial infections: ear infections, acute bronchitis in adolescents 

How does it work? 

• It kills bacteria by preventing bacteria from building cell walls and preventing bacterial cells from replicating. 
• Cefdinir is a “time-dependent killer” that stops bacterial infections slowly, so therapy is often long, around 7-10 days. 

What's the dose? 

• Varies depending on age, weight, and what you are treating
• The typical dose is 14 mg/kg/day up to the standard adult dose of 600 mg/day
• It can be given once daily or divided twice daily 

What are the most common side effects? 

• Diarrhea
• Rash (mild to severe)
• If the patient is also taking iron, stool can turn red 

How should my child take it? 

• Take with or without food, taking with meals may reduce stomach upset 
• Shake the suspension well and use the measuring device provided
• Do not take with antacids or iron (doses must be separated by at least 2 hours)
• Store the liquid suspension at room temperature

The information in this guide does not include a comprehensive list of all possible side effects, contraindications, or warnings associated with drug use. This content is for educational and entertainment purposes only and aims to quickly provide caregivers with the most common counseling points for pediatric medications. It does not replace professional medical advice, nor does it supersede information found on a pharmacy label or drug package insert. Always read the complete package insert before administering medication to your child. Consult your healthcare provider for medical guidance, and call 911 in case of an emergency. Kids Med Guide is not liable for your interpretation or reliance on this material. You assume full responsibility for its use and any resulting decisions. For details, please see our Privacy Policy and Medical Content Policy.

The following reference was used to compile this information:

DailyMed—CEFDINIR powder, for suspension. (n.d.). Retrieved June 18, 2025, from https://www.dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=7490df67-56c0-4a1c-8533-2107f3e8aea5