Med Minute: Amoxicillin

Med Minute: Amoxicillin
A doctor examining a boy's throat and the title: Med Minute: Amoxicillin

In this Med Minute guide, we’re covering amoxicillin, a commonly prescribed antibiotic used to treat and prevent various bacterial infections. It works by stopping bacteria from growing and replicating, often requiring a 7 to 10-day course for full effectiveness. Keep reading for quick facts on uses, dosing, side effects, and tips for giving it to your child!

What's it commonly used for?

  • Treating bacterial infections: ear infections, pneumonia, skin infections, urinary tract infections, strep throat, sinus infections, Lyme disease 
  • Preventing bacterial infections (prophylaxis): dental procedures, urinary tract infections, sickle cell disease 

How does it work? 

  • It kills bacteria by preventing bacteria from building cell walls and preventing bacterial cells from replicating. 
  • Amoxicillin is a “time-dependent killer” that stops bacterial infections slowly, so therapy is often long, around 7-10 days. 

What's the dose? 

  • Varies depending on weight and what you are treating
  • Typical doses are around 45 mg/kg/day (standard) or 90 mg/kg/day (high) up to standard adult doses of 500-1000 mg per dose
  • High dose regimen is most commonly used for ear infections or pneumonia 
  • Usually given every 8 or 12 hours

What are the most common side effects? 

  • Diarrhea, nausea, vomiting
  • Headache
  • Rash (mild to severe) 
  • Tooth discoloration

How should my child take it? 

  • Take with or without food, taking with meals may reduce stomach upset 
  • Shake the suspension well and use the measuring device provided
  • Store suspension in the refrigerator 
  • You can mix it with formula, juice, water, or milk, but make sure your child drinks the whole thing